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VDZ, a humanized IgG1 mAb, selectively blocks the 47 integrin from binding to MAdCAM-1 on intestinal endothelial cells, preventing lymphocyte transport to the intestine and promoting mucosal repair [188191]

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Semaglutide belongs to a class of drugs called GLP-1 receptor agonists, while tirzepatide is a dual GLP-1 and GIP receptor agonist

LFs therapeutic effects include mitigating CECs damage and promoting cellular repair, as demonstrated in animal models of DED (Pattamatta et al., 2013

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