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Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

Postmortem studies of PD brains have demonstrated microglial activation in the substantia nigra pars compacta (SNpc), characterized by increased expression of markers such as HLA-DR, CD68, and Iba-1, along with elevated production of pro-inflammatory mediators including IL-1, TNF-, IL-6, and reactive oxygen species (ROS) [73]

The authors reported a structure-activity relationship campaign over a library of acylated amylin analogs derived from the human amylin sequence

Healthy fats matter : Avocados, nuts, and seeds provide lasting energy and aid natural GLP-1 production

Practical Steps for Patients If you are considering or already on a GLP-1 medication: Get a baseline eye exam especially if you have diabetes