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However, in another intervention trial with combination therapy (53), the risk of adverse effects was significantly higher in the Se supplementation group, which we speculate may be related to unclear baseline Se levels in the subjects and a narrower safety window during Se treatment

It's not a dietary supplement either it's a synthetic compound that has never been approved for human consumption, so it's sold as a 'research chemical' labelled 'research use only.' That label is how sellers avoid making medical claims

Mitochondrial dynamics in mammals

Cholecalciferol is metabolized to its active form, calcitriol, which increases the bodys absorption of calcium and phosphorus